Alright, imagine you fall and scrape your knee. Your body is super smart, it sends tiny helpers called platelets to the injury to start fixing it. These platelets release special healing signals that tell your body to grow new skin and stop the pain.
PRF (Platelet-Rich Fibrin) is like a supercharged version of that healing process. We take a little bit of your blood, spin it down to isolate and collect the best healing parts, and then put it right where your body needs extra help, like a sore knee or a tiny wrinkle.
It’s like giving your body a boost of what it needs to heal faster and feel better, all using your own natural powers!
How PRF Therapy Works
Blood Collection – A small amount of the patient's blood is drawn, just like a routine blood test.
Centrifugation – The blood is spun at a lower speed, allowing the separation of platelets, white blood cells, and fibrin while retaining more growth factors. This process separates the PRF from the rest of the blood sample.
Fibrin Matrix Formation – PRF forms a gel-like fibrin matrix that releases growth factors over time, leading to longer-lasting regenerative effects.
Application – The PRF is extracted from the blood sample and is applied or injected into the treatment area, stimulating tissue repair and healing.
PRF (Platelet-Rich Fibrin) therapy is a regenerative treatment that uses the patient’s own blood to promote healing, tissue regeneration, and collagen production. PRF is considered a more advanced and effective alternative to PRP, Platelet-Rich Plasma (PRF's predecessor). PRF is especially effective for applications where a sustained release of healing factors is beneficial. It is widely used in regenerative medicine due to its natural composition and extended healing properties. PRF works by concentrating the body's natural healing factors, platelets, white blood cells, and fibrin, into a single injection. When placed at the site of injury, these growth factors accelerate tissue repair, reduce pain, and promote regeneration. By using your own blood, PRF enhances the body’s ability to heal itself without synthetic additives or foreign substances.
Read more about the components of PRF:
What is in PRF? What makes up PRF's gel-like Fibrin Matrix?
Benefits of PRF Therapy
Longer-Lasting Growth Factor Release – PRF releases healing proteins over several days, unlike PRP, which disperses quickly.
No Additives Needed – PRF is 100% natural and does not require anticoagulants like PRP does. PRF is not stem cell therapy and does not use any donated stem cells.
Higher Platelet and Leukocyte Concentration – This enhances its regenerative potential.
Versatile Applications – PRF is commonly used in:
Orthopedics & Sports Medicine – Treating joint injuries, tendonitis, muscular tears, Ligament injuries and osteoarthritis. How We Use It: At our office, we use PRF to accelerate healing from soft tissue injuries. Whether it's a strained muscle, tendon, or ligament issue, PRF injections can promote tissue repair and reduce pain. Using ultrasound guidance, we precisely inject the patient’s own PRF directly into the injured area, enhancing the body’s natural healing process. Most patients experience significant relief within 1 to 3 treatments.
Aesthetic Medicine – Facial rejuvenation (wrinkle reduction, increased collagen), hair restoration, scaring treatment. How We Use It: We combine PRF with microneedling to deliver growth factors into the top layers of the skin. This stimulates collagen production, improves skin texture, reduces wrinkles, and accelerates scar healing. PRF is also used for hair restoration, where it nourishes hair follicles and promotes natural regrowth.
Wound Healing – Improving recovery from chronic wounds and surgical incisions.
Other: Joint pain, Muscle strains, Rotator cuff tears. Achilles tendon ruptures, Ankle Sprain, Tendonitis, Tennis/Golfers elbow, Ligament damage, Soft tissue injuries, Hair growth, Erectile Dysfunction, Wrinkle reduction, Healing scar tissue
PRF is NOT the same as stem cell therapy
While PRF contains small amounts of mesenchymal stem cells, its primary mechanism of action is through platelet-derived growth factors, not stem cell regeneration. PRF enhances healing by stimulating the body’s natural repair processes rather than introducing new cells that differentiate into tissues.
Feature | PRF (Platelet-Rich Fibrin) | PRP (Platelet-Rich Plasma) | Outside Stem Cells |
Source | Patient’s own blood | Patient’s own blood | Donor tissue (placenta, umbilical cord) or lab-grown |
Processing | Spun at a lower speed, no anticoagulants | Spun at a higher speed with anticoagulants | Lab-processed before use |
Platelet Concentration | High, with slow-release growth factors | High, but releases growth factors quickly | Varies depending on the source |
Growth Factor Release | Slow, sustained release over days | Fast release, short duration | May contain growth factors, but focus is on stem cell differentiation |
Cell Types Present | Platelets, white blood cells, small amounts of mesenchymal stem cells | Platelets, little to no white blood cells | High concentration of donated stem cells |
Risk of Rejection | None (your own cells) | None (your own cells) | Potential (not your own cells) |
Common Uses | Joint & tendon injuries, facial rejuvenation, hair restoration | Joint injuries, aesthetics, wound healing | Severe injuries, degenerative diseases |
Read More in our Blog Post:
Watch our Patient Testimonials:
Is PRF Therapy right for you?
If you’re looking for a natural, non-surgical way to support healing, reduce pain, or enhance your skin and hair, PRF therapy may be the right choice for you. Whether you’re recovering from a joint injury, struggling with tendon pain, or seeking facial rejuvenation, PRF harnesses your body’s own healing potential to deliver lasting results.
At The Logan Institute, we specialize in cutting-edge regenerative therapies, using only your own cells to maximize safety and effectiveness. Our expert team will assess your condition and create a personalized treatment plan to help you feel and function at your best.
If you’re ready to take the next step toward healing, contact us today to learn more about how PRF therapy can work for you!
Comments